CT IMAGING OF MADELUNG DISEASE: A CASE REPORT

Authors

  • atchrin PEKANAN Department of Radiology, Ramathibodi Hospital
  • Supawadee PRAKUNHANGSIT Department of E.N.T., Ramathibodi Hospital
  • Supranee NIRAPATHPONGPORN Department of Radiology, Ramathibodi Hospital
  • Wiwattana THANOMKIAT Department of Radiology, Songklanakarin University Hospital

Abstract

Madelung Disease was first described by Launois and Bensaude in 1898 (1). Its synonyms are Launois-Bensaude disease, Buschke disease, cervical lipomatosis, Madelung neck and multiple symmetrical lipomatosis (2). It is characterized by progressive growth of fat masses which are located symmetrically at the neck, shoulders, chest, abdomen and groin (3). The disease seems to be more frequent in the Mediterranean regions, and approximately 97% of those affected are men.
We report a case of Madelung disease in a 38 years-old Thai male patient.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Launois PE, Bensaude R. De L. adeno-lipomatose symetrique. Bull Mem Soc Med Hop Paris 1898; 1:298-317 (Fre).

Taybi H, Lachman RS. Madelung disease: in Radiology of syndromes, metabolic disorders, and skeletal dysplasias, pp 282-283; 3rd Ed.1990 Chicago, Year book medical publishers, inc.

Enzi G, Biondetti RP, Fiore D, Mazzoleni F. Computed tomography of deep fat masses in multiple symmetrical lipomatosis. Radiology 1982; 144:121-124.

Enzi G, Inelmen EM, Baritussio A, et al. Multiple symmetric lipomatosis: a defect in adrenergic- stimulated lipolysis. J Clin Invest 1977;60:1221-1229.

Enzi G, Favaretto L, Dorigo P, et al. Defects of lipolysis in human lipomatosis. In: Enzi G, Crepaldi G, Pozza G, Renolds AE, eds, Obe- sity: pathogenesis and treatment. New York: Aca- demic Press, 1981:161-165.

Boonichon PH, et al: Maladie de Launois-Bensaude, Traitment par large cervicotomie trasversale. Presse Med. 1986:15:2247.

Buschke A, et al: Die traumatische Atiologie und die Begutachtung der symmetrischen Lipmatose. Klin. Wochenschr. 1929;8:880.

Enzi G, et al: Sensory, motor, and autonomic neuropathy in patients with multiple symmetric lipomatosis. Medicine (Baltimore) 1986;64:388.

Gate A, et al: Le syndrome de Launois-Bensaude: A propos de 12 cas cliniques, Ann. Chir. Plast. 1966;11:193.

Madelung O: Ueber den Fetthals (diffuses Liom des Halses). Arcj. Klin. Chir. (berlin) 1888;37:106.

Michon P. Adenolipomatose symetrique familiale. Presse Med 1936;44: 663-664 (Fre).

Kurzweg FT, Spencer R. Familial multiple lipomatosis. Am J Surg 1951;82:762-765.

McKusick VA. Mendelian inheritance in man.

Catalogs of autosomal dominant, autosomal recessive, and x-linked phenotypes. 5th ed. Baltimore: Johns Hopkins University Press, 1978:242-243.

Mounier-Kuhn P, Haguenauer JP, Localisation laryngree d une maladie de Launois Bensaude. J Franc Otorhinolaryngol 1967;16:603 (Fre).

Chahrokhi K, La Lipomatose symetrique diffuse a predominance cervicale. Rev Laryngol (Bor- deaux) 1960;81:551-578.

Comings DE, Glenchur H. Benign symmetric lipomatosis. JAMA 1968; 203:305.

Heitzman ER. The mediastinum. Radiologic correlations with anatomy and pathology. St. Louis, Mo:Mosby 1977.

Koerner HJ, Sun DI-C. Mediastinal lipomatosis secondary to steroid therapy. AJR 1966;98: 461-464.

Teates CD. Steroid induced mediastinal lipomatosis. Radiology 1970; 96:501-502.

Schuman BM. Mediastinal lipomatosis compli- cating steroid therapy of regional enteritis. Gastroenterology 1971;61:244-246.

Bodman SF, Condemi JJ. Mediastinal widening in iatrogenic Cushing's syndrome. Ann Intern Med 1967;67:399-403.

Santini LC, Williams JL. Mediastinal widening (presumable lipomatosis) in Cushing's syndrome. N Engl J Med 1971;284:1357-1359.

Price JE Jr, Rigler LG. Widening of the mediasti- num resulting from fat accumulation. Radiology 1970;96:497-500.

Steckel RJ. Mediastinal pseudotumors associated with exogenous obesity. Radiology 1976;119:74.

Lee WJ, Fattal G. Mediastinal lipomatosis in simple obesity. Chest 1976;70:308-309.

Downloads

Published

2023-03-30

How to Cite

1.
PEKANAN atchrin, PRAKUNHANGSIT S, NIRAPATHPONGPORN S, THANOMKIAT W. CT IMAGING OF MADELUNG DISEASE: A CASE REPORT. ASEAN J Radiol [Internet]. 2023 Mar. 30 [cited 2024 Dec. 11];1(2):17-9. Available from: https://www.asean-journal-radiology.org/index.php/ajr/article/view/234

Issue

Section

Original Article